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The most common adverse effects from the SURMOUNT trials include: Nausea: 24-33% of participants (dose-dependent) Diarrhea: 18-25% of participants Constipation: 13-17% of participants Vomiting: 8-12% of participants Decreased appetite: 10-15% of participants Most of these effects are mild to moderate and occur primarily during dose escalation periods

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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 12 Dual GIPGLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential Authors Bastin M , Andreelli F Received 12 May 2019 Accepted for publication 17 August 2019 Published 30 September 2019 Volume 2019:12 Pages 19731985 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Konstantinos Tziomalos Marie Bastin, Fabrizio Andreelli Diabetology-Metabolism Department, Sorbonne Universit, ICAN, Assistance Publique Hpitaux de Paris, Piti-Salptrire Hospital, Paris, F-75013, France Correspondence: Fabrizio Andreelli Diabetology-Metabolism Department, Piti-Salptrire Hospital, 47-83 Boulevard de lHpital, Paris cedex 13, 75951, France Email [email protected] Abstract: The need for efficient and safe therapy to improve such metabolic diseases as obesity and type 2 diabetes mellitus is currently unmet

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