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The blood pressure-lowering effects likely result primarily from weight loss, which reduces cardiac workload and peripheral vascular resistance , leading to decreased blood pressure through hemodynamic changes

Future research is expected to expand on this paradigm through the development of triple agonists targeting additional metabolic pathways, exploration of oral and long acting formulations, and refinement of patient selection criteria to maximize clinical benefit while minimizing risk

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Accessing microdose concentrations Standard pharmaceutical GLP-1 products are not designed for microdosing