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In vitro , ferroptosis activates inflammatory responses in microglia, and the systemic inflammation caused by LPS stimulation can be partially inhibited by Fer-1 (151)

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They warn that the lack of rigorous clinical trials and standardized protocols raise serious safety concerns, including the risk of hepatotoxicity (liver damage caused by chemicals) and allergic reactions like anaphylaxis

Plus, LL-37 could be protumorigenicmeaning it could cause tumors to developin some tissues