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It increases skeletal muscle protein synthesis and can help prevent bone loss in older age (especially in postmenopausal women who are at the highest risk of bone-related disorders like osteoporosis)

Introduction GLP1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) work by mimicking a hormone your body already makes called glucagon-like peptide-1

These medications, including semaglutide, liraglutide, dulaglutide, and now tirzepatide, demonstrate safety even in higher-risk groups

While not specifically studied with tirzepatide, changes in appetite-regulating hormones that also influence sleep-wake regulation could hypothetically contribute to altered sleep quality during active weight loss phases