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In this study, it was shown that TC10 existed in the Arf6-containing endosomes, and the expression of a dominant negative TC10 in the hippocampal neuron culture resulted in decreased surface/total AMPAR ratio, whereas constitutively active TC10 increased the ratio (Zheng et al., 2015)

Blockade of the Interleukin-7 Receptor Inhibits Collagen-Induced Arthritis and Is Associated With Reduction of T Cell Activity and Proinflammatory Mediators

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This process reprograms the suppressive tumor microenvironment, characterized by increased DC maturation, elevated CD8 T-cell infiltration, and a reduction in regulatory T cells