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Contact pairs were grouped across ligand-bound structures to uncover pairs that were either shared across all structures (universal) or limited to subgroups, such as active, inactive, biologic-bound or drug-specific structures (Fig

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The 13 C-NMR measurements together with the infusion of 13 C-labeled substrates in mice (60), rats (163) and human (166) have shown that neuronal mitochondrial TCA cycle in the cerebral cortex contributes ~7085% of the total energy produced and the remaining (~1530%) by astroglia