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In a clinical trial, pure genistein supplementation (54 mg/day, P.O for one year) improved both cardiac function and left atrial remodeling in postmenopausal women with metabolic syndrome [138]

Here, we present a 19-year-old female who was diagnosed with glutathione synthetase deficiency shortly after birth and who has been closely followed in our metabolic clinic

Gastrointestinal side effects may complicate disease assessment in conditions like inflammatory bowel disease, and drug interactions with immunosuppressants should be considered

One potential limitation of this study was the lack of assessment of active GSH levels and relationship between plasma and liver GSH levels during GSH resynthesis