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Methods: We conducted a retrospective study including 22 clinical and radiological variables from medical records of patients undergoing MT between April 2016-April 2024

Meta-analysis was performed using a random-effects model, with 13 eventually meeting the inclusion criteria

Melanin is a naturally occurring pigment that is produced by specialised skin cells known as melanocytes

As an organic salt, CM and is formed through the combination of L-citrulline (C 6 H 13 N 3 O 3 ), a non-essential amino acid involved in the urea cycle, and malate (or malic acid, C 4 H 6 O 5 ), a tricarboxylic acid (TCA) intermediate (Bendahan et al