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Acknowledgements Authors wish to thank Molecular Medicine Department and also Pharmaceutical Sciences Research Center of Shiraz University of Medical Sciences

ROS can target several different substrates in the cell, causing protein, DNA, and RNA oxidation or lipid peroxidation [99]

It is important to note that long-term use can lead to dependence and withdrawal symptoms

In 2 large trials totaling over 5,900 healthy older adults followed for 5 to 6 years (GEM and GuidAge), ginkgo did not prevent dementia or slow cognitive decline