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The researchers proceeded in three steps: Emulated two major randomized controlled trials (SUSTAIN-6 for semaglutide vs placebo and SURPASS-CVOT for tirzepatide vs dulaglutide) to validate methods

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How did you get on this science, the track that you became on

Conceptual Origin: From Empirical Observation to Theoretical Framework In the 16th century, the Swiss physician Paracelsus established the philosophical foundation for dose-response relationships with his statement, The dose makes the poison ( Sola dosis facit venenum )