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doi:10.1016/j.eclinm.2021.101080

Lets talk about what we actually know: The Biology: GLP-1 receptors are expressed throughout the body, including on immune cells, endothelial cells (lining blood vessels), neurons, and adipose tissue

The studies presented other limitations, such as (a) heterogeneity, (b) varied doses and routes of melatonin administration, (c) a lack of measurement of the plasma melatonin levels for evaluation and comparison, and (d) a lack of blinding of the evaluators