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These are not GLP-1 side effects and may signal heart, lung, or allergic conditions requiring urgent diagnosis

However, the clinical significance of the observed changes in insulin and glucose levels needs to be assessed in longer-term studies

Patients with concerning symptoms such as dysphagia at any age, or those aged 55 and over with weight loss and upper abdominal pain, reflux or dyspepsia should be referred urgently to exclude upper GI malignancy, in line with NICE guidance (NG12)

The PlexusDx semaglutide option PlexusDx provides semaglutide through its Weight Management Protocols, offered as Semaglutide Injection at $189 per month and Semaglutide Oral, alongside the Precision Peptide Genetic Test