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PMID: 25649658
Bobot, M
On the other hand, the treatment policity estimand was used to evaluate the treatment effect for all randomized participants regardless of whether the trial was discontinued early or rescue medicien was used [2]
Phase I data presented at the American Heart Association (AHA) 2025 meeting and published in The New England Journal of Medicine ( NEJM ) showed deep, dose-dependent reductions in ANGPTL3 (up to 89%) with corresponding decreases in triglycerides and LDL cholesterol, including in patients already on standard lipid-lowering therapy
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