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Muscle loss during GLP-1 weight loss is typically linked to: Low protein intake Large calorie deficits Reduced resistance training Rapid or unstructured weight loss Weight loss always includes a mix of fat and lean mass loss, but research on GLP-1 medications suggests that while fat loss is predominant, some lean mass loss can occur depending on dietary intake and physical activity levels
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Moreover, retinal protection was achieved without affecting systemic blood glucose levels in this study, suggesting the protective effects of GLP-1 are independent of blood glucose or insulin [80]
doi: 10.1016/j.intimp.2014.07.010 157 RichterGFeddersenOWagnerUBarthPGkeRGkeB
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