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As GLP-1 induced cutaneous reactions are diverse, diagnosis requires clinical suspicion, thorough history-taking, and supportive histopathological findings when available

For higher-risk patients, the tools shift: a liquid-only diet for the 24 hours before surgery, an anesthesia plan adjusted for the possibility of a fuller stomach, and in some cases a point-of-care gastric ultrasound to look at whats actually in there before proceeding

Long-term trials confirm it can still deliver meaningful and sustainable benefits for many patients

For example, SubMagnaTM SL HMW can be used to deliver semaglutide in a sublingual dosage form