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Simple timing framework Baseline Discuss baseline labs before starting, especially with active injury, infection concern, liver disease, kidney disease, anemia, or copper metabolism concerns

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Multivariable logistic regression analyses were performed to predict favourable outcome at 3 months (defined as mRS 0-3) and mortality, adjusted for confounders at admission (age, prior mRS, NIHSS score, ICH volume, intraventricular haemorrhage, infratentorial location), CBP achievement, and OTA times