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LTF can also be synthesized by pro-inflammatory activated microglia (Fillebeen et al., 2001), and may also be related to the iron disturbances in the AD brain with senescent iron-accumulating microglia and lipid-rich microglia (Zeineh et al., 2015

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In dual-agonist and triple-agonist research, it may contribute to a broader incretin response than GLP-1 alone

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