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For long-acting agents such as semaglutide, clinicians generally recommend stopping therapy at least two months before attempting pregnancy due to the extended half-life

However, constipation often tends to be more persistent than other GI side effects, with some studies indicating it can last for weeks, or even months, for some individuals

Our ambition with this app is to raise the standard of day-to-day support as more people use GLP-1s as a part of their weight loss journey

2 Cell-penetrating peptides as novel carrier molecules CPPs, usually 5-30 amino acids-long peptide moieties (Kurrikoff et al., 2021), are not only able to pass through the plasma barrier but also capable of facilitating the cellular transport of drugs and other conjugated or coadministered cargos (Liu et al., 2022)