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If the issue is pigmentation, standard treatments include oral medications such as Vitamin C, E, and tranexamic acid, topical brightening agents like hydroquinone, and light or laser therapies

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Oral, liposomal, or topical options may be preferred for many patients because they are gradual and easier to maintain, while IV glutathione should be considered only after proper medical evaluation and under qualified supervision

For quantitative fluorescence measurement, cells were lysed with 1 N NaOH, and fluorescence intensity (Excitation at 485 nm, Emission at 535 nm) was measured using a microplate reader (Tecan, Oberdiessbach, Switzerland)