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Diet-induced obesity (DIO) mice were generated by starting a high-fat diet (HFD-60, lipid 60 kcal%, Oriental Yeast) feeding for C57B6J (B6) mice (Oriental Yeast) at six weeks of age

But based on the $4.1 billion estimate, the range of the grants could be $175 million to $200 million total over the 12-year period, Johnson said