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Weeks 5 to 8: Dose Changes and Common Patterns Weeks 5 to 8 often include dose adjustments in many treatment plans

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As a result of these beneficial effects of GLP-1R activation on metabolism, several drugs acting on the GLP-1R have been developed for the treatment of T2DM and obesity, including the GLP-1RAs liraglutide and exendin-4 or its synthetic version exenatide, and additional products are in different stages of development (Nauck et al., 2016

Other benefits included a reduction in glycated hemoglobin (HbA1c) by 0.6%, low-density lipoprotein (LDL) cholesterol by 18 mg/dL, triglycerides by 29 mg/dL, systolic blood pressure by 9 mm Hg, and diastolic blood pressure by 2 mm Hg, demonstrating the benefits of pharmacists' involvement (Yates et al