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Evans blue concentration was determined by spectrophotometric measurement at 620 nm and expressed as g/g gingivomucosal tissue as described earlier by our group (6)

The rats were divided into 3 groups: topical TCC (blue copper peptide), topical TCC carrier (hydroxypropyl methylcellulose), and no treatment (control)

Reported effects may include: Mild bloating or stomach discomfort Nausea Headache Skin rash Unpleasant taste (with sublingual use) Stop the medication and contact your provider promptly if you develop: Persistent abdominal pain or vomiting Wheezing or shortness of breath Severe rash or swelling Any unusual or worsening symptoms Trouble breathing Swelling of face, lips, or tongue Severe allergic reaction Chest pain, severe dizziness, or fainting Take exactly as prescribed

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells