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Clinical trials demonstrate GLP-1 efficacy in reducing HbA1c, cardiovascular events, and metabolic dysfunction regardless of baseline weight

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A groundbreaking study has unveiled that lactylation of the Lys131 residue at the N-terminus of cGAS by AARS2 in the wake of viral infection leads to a loss of DNA recognition capacity

This confirms that GABAergic neurotransmission deficits are present as early as the early postnatal period in the En2 mouse model of ASD, highlighting the potential role of neurodevelopmental defects in GABAergic interneurons in the pathogenesis of ASD (109)