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As early as 1959, Rosenberg and Culik [ 28 ] suggested the protection of other antiox- idants by ALA demonstrating that ALA is able to prevent symptoms of both vitamin E and vitamin C deciency

Ozone Ther Global J 13(1):175197 Ighodaro O, Akinloye O (2018) First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid

While overall incidence has declined in older adults, rates are rising sharply among younger people