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This was followed by active clinical development for the treatment of several autoimmune diseases, and the first indication for which efgartigimod entered late-stage clinical trials was gMG, which was found to be ameliorated by intravenous (i.v.) delivery of efgartigimod in a pivotal, proof-of-concept, phase II study in 2019 [227]

Mutual-Support Groups Mutual-support groups, such as Alcoholics Anonymous (AA), are group meetings of peers who can provide each other with support for limiting or stopping drinking

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Under resting condition, Nrf2 activity is inhibited by KEAP1 and maintained at a basal level