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One study showed that arginine was not helpful and may have even been harmful when used for treating heart attacks in combination with standard treatment
Advances in Bioscience and Biotechnology, 03 (07), 9971019
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Compared to enzyme-cleavable linkers, chemically cleavable linkers offer more consistent performance across different patients and tissues, making them especially suitable for ADC designs requiring precise control of drug release rate and location, thereby improving therapeutic outcomes and lowering side effect risks
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