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The subcutaneous injection of any medication can trigger a localised inflammatory response as the body processes the foreign substance, but this does not indicate an allergic reaction in most cases

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Intriguingly, supplementation with mitochondria-targeted TEMPO (mitoTEMPO), which accumulates in active mitochondria where the reduction of its active nitroxide to hydroxylamine is mainly mediated by ubiquinol 35 , also significantly rescued survival upon LDHB silencing (Fig