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Questions in domain one assessed the randomization process for selecting the subjects in each trial, while domain two reviewed if there were any deviations from the intended interventions

I.V., Intravenous

When GSH regeneration is further limited by inhibition of SLC7A11 (with erastin), cell death ensues

Their anti-atherogenic effects together with plaque stabilization capabilities along with decreased vascular inflammation and enhanced lipid profiles make them an ideal choice for secondary prevention [9,24]