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A meta-analysis of randomized controlled trials comparing GLP-1 RAs and SGLT2is in patients with obesity and T2D uncontrolled on metformin found that GLP-1 RA use was associated with significantly reduced HbA1c ( 0.40%

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2,4 Ideally patients would consume the minimum amount to maintain a steady state neutrophil vitamin C concentration with minimal excess renal excretion