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Unlike other compounds that act on the vascular system, PT-141 is unique in that it exerts its influence via the central nervous system, stimulating melanocortin receptors, particularly MC3R and MC4R, which are involved in modulating sexual behaviour and mood in various animal and human studies

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It can be attributed to the ability of these skin regions in vitamin D, different cytokines, and various growth factors production (Abdel-Naser et al., 2012)

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