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Recent studies have shown that iron release via NCOA4-mediated ferritinophagy supported synthesis of ISC proteins and mitochondrial respiration, which are critical for PDAC growth [6]

The intervention group received 600 mg of NAC twice daily for 8 weeks, and the control group received a placebo with the same prescription form

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This contrasts sharply with orthobiologic therapies like PRP and mesenchymal stem cell therapies, both of which have been evaluated in multiple randomized controlled trials and large observational studies