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After rinsing, the glass coverslip was transferred to the recording chamber mounted on an inverted microscope (Leica, DMIRB) and continuously superfused with the extracellular medium described above without adding MgSO4 (Mg 2+ ions free medium)

When administered to rats within 30 minutes of experimental acetaminophen intoxication, 200 mg/kg of curcumin prevented the microscopic appearance of kidney damage, prevented elevations in renal lipid peroxidation, and maintained glutathione levels compared to control rats (Cekmen 2009)

FIGURE 3 Undoubtedly, the GliT-mediated self-resistance mechanism (Schrettl et al., 2010

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