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SPMs can decrease levels of pro-inflammatory cytokines, such as IL-1, IL-6, and tumor necrosis factor (TNF)-, through activating their G protein-coupled receptors, thus causing activation of anti-inflammatory transcription factors, such as peroxisome proliferator-activated receptor gamma, and down-regulating intracellular NF-kB signaling pathway (14, 63)

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Warning signs that warrant immediate medical evaluation include frequent dehydration episodes, inability to retain fluids, vomiting material that resembles coffee grounds or contains blood, intense abdominal pain, or unplanned weight loss

Supports Immunity:Studies show increases immune cells in addition to being vital to T-Cell function