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Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R

Statutory health insurance is firmly anchored in the German health system: Around 90% of the German population (around 73 million) are insured with one of the 105 statutory health insurance companies (in 2020)

Recent studies indicate its potential role in stem cell biology and anti-tumor research as well