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The semaglutide titration protocol used in the STEP trials and embedded in the Wegovy prescribing information is designed to bring researchers to the 2.4 mg maintenance dose over 16 weeks while keeping gastrointestinal side effects manageable
Beginners should commit to at least 812 weeks to begin seeing changes, and 1624 weeks for significant visceral fat reduction
They are not mutually exclusive a researcher can run 5-on/2-off within an 812 week block and still take the 4-week macro-break afterward
Here we focus specifically on IV vitamin therapy, which involves delivering one or more vitamins to the body
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