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also an oral form Rybelsus ), Liraglutide ( Victoza for diabetes, Saxenda for weight loss), Dulaglutide ( Trulicity ), Exenatide ( Byetta short-acting, Bydureon long-acting), Lixisenatide ( Adlyxin ), and newer dual-agonist drugs like Tirzepatide ( Mounjaro ), which activates the GLP-1 receptor and the GIP receptor (another incretin hormone) All of these medications work in a similar physiological manner by leveraging the GLP-1 pathway to improve glycemic control and suppress appetite

Medical history: gallbladder disease, pancreatitis, kidney issues, or eating disorders change the risk discussion

Afamelanotide activates the melanocortin-1 receptor on pigment-producing melanocytes and increases production of eumelanin, the darker form of melanin