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Very grateful to ed silverman for making the introduction to the wonderful Torie Bosch at STAT
In SURPASS-1 (Rosenstock et al., Lancet 2021), GI event rates clustered in the dose-increase months and declined for people who stayed on the medication past the initial adjustment period
For example, some medications can impact digestion or absorption in ways that may interact with GLP-1 activity
Anxiety was the most central symptom within the symptom network at T1 (Strength = 2.134, Closeness = 0.127, EI = 2.134), while depression held the central position at T2 (Strength = 2.595, Closeness = 0.157, EI = 2.595), T3 (Strength = 2.689, Closeness = 0.161, EI = 2.689), and T4 (Strength = 2.789, Closeness = 0.172, EI = 2.789)
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