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A liver biopsy was performed, which revealed mild to moderate mononuclear cell infiltrate within the hepatic lobules and portal tracts, along with multiple large foci of hepatic necrosis exhibiting a mixed periportal and centrilobular pattern consistent with acute hepatitis

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GLP-1 RAs may also reduce the number of dermal -T cells and IL-17 mRNA expression in psoriasis plaques in patients with diabetes [13, 22]

STEP 1, the largest trial with 1,961 participants, demonstrated that after 68 weeks of treatment, patients achieved an average weight loss of 14.9% compared to 2.4% with placebo