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Therefore, pathogenic variants in either of these genes will result in defective or reduced methylmalonyl-CoA mutase activity leading to methylmalonic acidemias

Recommended Storage Guidelines Lyophilized powder is generally stable for extended periods when stored at 20C , protected from light and moisture

As tirzepatide clears over 3-4 weeks, gastrointestinal symptoms typically improve gradually, appetite may return, and blood glucose levels may rise in patients with diabetes