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TXNRD1 has emerged as a selective vulnerability in KRAS -wild-type and KRAS inhibitor-resistant tumors, where its blockade induces ferroptosis through combined GSH depletion and iron overload 117

Furthermore, the band at 567 cm 1 can be attributed to the FeO stretching vibration of the tetrahedral sites in the spinel structure, while the band at 441 cm 1 is associated with the tetrahedral and octahedral sites (He et al

By efficiently lowering lipid peroxidation (as indicated by reduced MDA levels) and improving antioxidant defense mechanisms (as shown by enhanced GPx activity), the NP formulations may help attenuate oxidative damage and promote liver regeneration [73]

Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy