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Lifestyle factors: The FDA has approved semaglutide (Wegovy) for chronic weight management and type 2 diabetes management combined with a healthy diet, increased physical activity and exercise

On average, participants lost about 15% of their total body weight over a 68-week period

Due to these findings, oral Wegovy would currently be my preferred choice when cardiovascular risk reduction is top priority, says Anton, noting that both medications seem promising for people focused primarily on blood glucose control or creating modest improvements in blood pressure and cholesterol

Weeks 13 to 16 (1.7 mg, 34 units at 5 mg/mL): Weight loss accelerates