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Any disorder, unwillingness or inability not covered by any of the other exclusion criteria, which, in the investigators opinion, might jeopardize the participants safety or compliance with the protocol

Anecdotal reports Longer schedules, including 12-16 week cycles, are reported online but have even less direct evidence behind them

Claims that B12 shots enhance energy, improve mood, or facilitate weight loss in people without deficiency are not supported by high-quality clinical trials

They support general mitochondrial function by increasing a crucial coenzyme but do not directly address cardiolipin damage or membrane structure