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(2025) 17:e78050

Targeted cells were subsequently differentiated into CMs, and these cells indeed showed a rescue of the disease phenotype including the absence of Gb3 accumulation and hypertrophy

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GLP-1RA has been placed prominently in the international recommendations for the treatment of T2D as the first injectable agent before insulin due to the advantageous outcomes in cardiovascular safety studies that demonstrated a reduction of the combined cardiovascular endpoint three-component major adverse cardiovascular event (MACE-3