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Description

Silymarin protects against acute liver injury induced by acetaminophen by downregulating the expression and activity of the cyp2e1 enzyme

Scientific Reports 8 , 13304, (2018)

Mechanism: cyclooxygenase pathway cyclooxygenase pathway NSAIDs exert their effects, primarily, through the inhibition of cyclooxygenase (COX)-induced conversion of arachidonic acid to prostaglandins and thromboxane