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Notably, previous MRS studies in ASD, predominantly conducted using 1.53 T MR scanners, have not succeeded in quantifying the metabolite levels, resulting in inconsistent findings [21,22,23,24,25,26]

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Importantly, ZXGD could decrease these adverse factors such as HIF-1, ROS, IL-6, IL-1 and TNF-, while increase beneficial factors such as Nrf2 and IL-10, to relieve hypoxia, oxidative stress and inflammation to ameliorate pulmonary vascular remodeling in PH rats

It's like sending out delivery trucks that are too big to navigate the narrow city streets