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Nausea Vomiting Heartburn Abdominal discomfort Diarrhea Constipation Bloating Indigestion Burping Fatigue Headache Mild redness, itching, or soreness at the injection site Less Common but Important Risks Gallbladder disease or gallstones requiring removal of gallbladder Delayed stomach emptying (gastroparesis) Pancreatitis Kidney Considerations Severe dehydration related to persistent vomiting or diarrhea may increase the risk of acute kidney injury

This topical option is applied to the skin and delivers steady hormone levels throughout the day

This combined approach allows researchers to examine potential synergistic effects beyond single-pathway activation

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