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Zhezhe Cui, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

1 Introduction Fatigue is a common chronic cross-diagnostic symptom (5) and in fibromyalgia patients ( In CFS, fatigue of unknown origin is a hallmark diagnostic feature ( In hypothyroidism, about 15 20% of patients report fatigue or brain fog even after correction of thyroxine levels to normal with levothyroxine ( L-carnitine supplementation has been suggested to reduce fatigue in both hypothyroidism ( 2 Materials and methods 2.1 Study design and participants The present study is a retrospective analysis of follow-up clinical data