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Thirdly, we discovered several microbial proteins that contribute to bacterial virulence and potentially induce gallstone formation, such as Buchnera lepA, RtxA gene, pckA gene, Tuf, and TpiA

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In addition, PBH is characterized by reduction in fasting plasma levels of amino acids (AAs), multiple lipid species, and tryptophan intermediates including kynurenate, xanthurenate, and serotonin