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Arch Pharm Res 43(5):514525 Abdelhamid AM, Elsheakh AR, Abdelaziz RR, Suddek GM (2020) Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-B/Nrf-2/PPAR- interplay in mice
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The mechanism appears to involve increased serotonin synthesis in substantia nigra (both compacta and reticulata), a regional pattern unlike any existing antidepressant drug, plus potential dopaminergic contributions given the nigrostriatal location
What India needs now is coordinated education at scale from KOLs to practitioners to patient support programs before the category can truly realise its potential
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