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This article examines the evidence for visceral fat reduction with GLP-1 therapy, the mechanisms involved, and clinical implications for patients with central obesity and cardiometabolic disease

The lysate was subsequently clarified by centrifugation at 16 000 g and 4 C for 30 min and subjected to partial purification by wheat germ agglutinin-agarose treatment

Patients should be educated about potential symptoms of thyroid tumors, including persistent hoarseness, difficulty swallowing, or a neck mass, though these symptoms are rare and may have many other causes

These comparative results align with the arm-level results for respective trials, with liraglutide having the smallest change from baseline (range 6.6% to 9.2%), followed by tirzepatide 5 mg ( 16.0%), semaglutide (range 16.6% to 17.1%), tirzepatide 10 mg ( 21.4%) and tirzepatide 15 mg ( 22.5%) (Supplementary Material Table S9)